Allegra

Fexofenadine hydrochloride, the major active metabolite of terfenadine, is an antihistamine with selective peripheral H1-receptor antagonist activity. Both enantiomers of Fexofenadine hydrochloride displayed approximately equipotent antihistaminic effects. Fexofenadine hydrochloride inhibited antigen-induced bronchospasm in sensitized guinea pigs and histamine release from peritoneal mast cells in rats. The clinical significance of these findings is unknown. In laboratory animals, no anticholinergic or alpha1-adrenergic blocking effects were observed. Moreover, no sedative or other central nervous system effects were observed. Radiolabeled tissue distribution studies in rats indicated that Fexofenadine does not cross the blood-brain barrier.

If you are taking fexofenadine and pseudoephedrine 12-hour tablets, you may notice something that looks like a tablet in your stool. This is just the empty tablet shell, and this does not mean that you did not get your complete dose of medication.

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Symptoms of overdose may include:

• dizziness
• drowsiness
• dry mouth
• giddiness
• headache
• nausea
• vomiting
• sweating
• thirst
• fast or pounding heartbeat
• chest pain
• difficulty breathing
• difficulty urinating
• muscle weakness or tenseness
• nervousness
• restlessness
• difficulty falling asleep or staying asleep
• hallucinating (hearing voices or seeing things that do not exist)
• seizures
• coma