Archive for November, 2008

Fexofenadine History

Sunday, November 30th, 2008

The older antihistaminic agent terfenadine was found to metabolize into the related carboxylic acid, fexofenadine. Fexofenadine was found to retain all of the biological activity of its parent while giving fewer adverse reactions in patients, so terfenadine was replaced in the market by its metabolite.[5] Fexofenadine was originally synthesized in 1993 by Massachusetts-based biotechnology company Sepracor, which then sold the development rights to Hoechst Marion Roussel (now part of Sanofi-Aventis), and was later approved by the Food and Drug Administration (FDA) in 1996. AMRI holds the patents to the intermediates and production of fexofenadine HCl along with Roussel. Since that time, it has achieved blockbuster drug status with global sales of $1.87B USD in 2004 (with $1.49B USD coming from the United States). AMRI received royalty payments from Aventis that enabled the growth of AMRI.

How Allegra taken?

Sunday, November 23rd, 2008

Take this Allegra medication by mouth on an empty stomach 1 hour before or two hours after meals as directed, usually twice daily. Taking this Allegra medicine with a high fat meal can decrease its effectiveness. Do not take antacids containing aluminum and magnesium within 2 hours of taking this Allegra medication. Swallow the Allegra medicine whole. Do not crush or chew the Allegra tablet, and do not take more than prescribed. Do not take this Allegra product within 14 days after stopping an MAO Inhibitor.

Allegra - Say goodbye to allergies

Tuesday, November 11th, 2008

Allegra is effectively used to treat allergic symptoms like itchy red eyes, stuffy nose and throat irritation. It contains antihistamine and decongestant, and can be consumed orally on an empty stomach 1 to 2 hours before lunch, twice daily.

Allegra is recommended that you avoid high fat meal while consuming these tablets as they could slower the effectiveness of this medicine. It is necessary that take the dosage as prescribed by your doctor and should be swallowed in entirety. Please do not crush or chew the tablets or take more than prescribed. Avoid taking antacids containing aluminum and magnesium within 2 hours of taking this medication or within 14 days after stopping an MAO Inhibitor.

Please inform your doctor if you have a medical history of allergies, kidney/urinary problems, enlarged prostate, glaucoma (narrow angle), severe high blood pressure, heart disease, diabetes, thyroid problems (hyperthyroid). The consumption of alcohol is also not permissible when taking this drug as it could aggravate its side effects.

Please avoid the usage of this drug during pregnancy or breast feeding. If it is very necessary to consume the same please consult your doctor or medical practitioner before using the same. Also inform your doctor if you are planning to take or are already taking any prescription or nonprescription drug.

On event of an overdose please contact your local poison control center or hospital immediately. A few of the symptoms of overdose may include irregular or unusually slow or fast heartbeat, unusual nervousness or excitement, rapid breathing, confusion, hallucinations, and seizures.

Some moderate side effects like nausea, stomach upset, trouble sleeping, headache, or cold symptoms may occur. If these persist or worsen, notify your doctor immediately. If you find any of the symptoms not listed above please get in touch with your doctor immediately.