Archive for December, 2008

Allegra Overdose

Saturday, December 27th, 2008

Reports of fexofenadine overdose are infrequent, and because of this, the effects are not well established. No deaths occurred in testing on mice, at 5000 mg/kg, which is 110 times the maximum recommended dose for an adult human. Further research shows no deaths in rats at the same concentration, which equates four hundred times the recommended dose in an adult human. Research on humans ranges from a single 800 mg dose, to a twice-daily 690 mg dose for a month, with no clinically significant adverse effects, when compared to a placebo.

How Do Antihistamines work?

Saturday, December 20th, 2008

Antihistamines are the antidote to exposure to histamine. As their name
implies, antihistamines are able to block the effects of histamine in your
body. [You should think of antihistamines as being the bouncer at
a club].

When histamine molecules get onto the surface of the cell, they cause
inflammation and irritation.

Antihistamines displace the histamine molecules from the cell and form
a protective shield around the cells so that histamine can not interact
with the cell to cause an allergic reaction.

Allegra Reported Results

Thursday, December 11th, 2008

1.

Benefits: Allergic reactions stopped almost immediately
Side effects: Very dry skin and hyperactivity
Comments: Took medication when symptoms arose, stopped when subsided
2.

Benefits: It helps with sneezing but my nose runs like a faucet. It relieves my itching eyes, I don’t cough as much.
Side effects: none - I don’t recall anything
Comments: I’ve struggled with allergies for 20 yrs. Very few drugs help me however this drug does at least slow down the reaction to allergins. I’m going to try Zyrtec now that it is OTC. I’ve tried benedryl and claritin which don’t help.
3.

Benefits: I had terrible itching, watery eyes, and sneezing from seasonal allergies. This medication did not completely elimiate my symptoms, but is reduced them to a tolerable level without making me too tired or doped up to function at work.
Side effects: I think I did experience some drowsiness from the medication, but nothing that was overly so such that I could not function at work.
Comments: The doseage was one pill/day